Anti-promastigote activity of the amazon plants

Silva-Silva, Jo?o Victor; Monteiro, R. C. S.; Brigido, H. P. C.; Vale, Valdicley Vieira; Silvestre, J. V.; Silva, N. C. S.; Silveira, Fernando Tobias; Marinho, A. M. R.; Dolabela, Maria Fani

Artigo

Anti-promastigote activity of the amazon plants

This study evaluated in vitro activity of ethanol extract, fractions, and isolated substance from Amazon species against promastigotes of L. amazonensis. The ethanol extracts were concentrated and fractionation. The anti-promastigote activity was evaluated through the cell viability assessment met...

ver descrição completa

Autor principal:	Silva-Silva, Jo?o Victor
Outros Autores:	Monteiro, R. C. S., Brigido, H. P. C., Vale, Valdicley Vieira, Silvestre, J. V., Silva, N. C. S., Silveira, Fernando Tobias, Marinho, A. M. R., Dolabela, Maria Fani
Grau:	Artigo
Idioma:	eng
Publicado em:	David Publishing 2019
Assuntos:	Fitoterapia / m?todos Plantas Medicinais / qu?mica Extratos Vegetais / qu?mica Leishmania / efeitos dos f?rmacos Himatanthus articulatus Fasciculata parahancornia Montrichardia linifera Physalis angulata
Acesso em linha:	http://patua.iec.gov.br//handle/iec/3692

id	ir-iec-3692
recordtype	dspace
spelling	ir-iec-36922019-05-17T11:46:04Z Anti-promastigote activity of the amazon plants Silva-Silva, Jo?o Victor Monteiro, R. C. S. Brigido, H. P. C. Vale, Valdicley Vieira Silvestre, J. V. Silva, N. C. S. Silveira, Fernando Tobias Marinho, A. M. R. Dolabela, Maria Fani Fitoterapia / m?todos Plantas Medicinais / qu?mica Extratos Vegetais / qu?mica Leishmania / efeitos dos f?rmacos Himatanthus articulatus Fasciculata parahancornia Montrichardia linifera Physalis angulata This study evaluated in vitro activity of ethanol extract, fractions, and isolated substance from Amazon species against promastigotes of L. amazonensis. The ethanol extracts were concentrated and fractionation. The anti-promastigote activity was evaluated through the cell viability assessment method (MTT). The ethanol extract, fractions, and isolated substance from Himatanthus articulatus and Parahancornia fasciculata were inactive in promastigote of L. amazonensis, as the ethanol extract of Physalis angulata. The hexane fractions from different parts of Montrichardia linifera showed anti-promastigote activity probably due to the presence of steroids and terpenes. All species in studies were inactive, except of M. linifera. The few polar constituents can be responsible for the activity. Therefore, the isolation and purification of the active on L. amazonensis promastigotes are urgently required. 2019-05-17T11:18:17Z 2019-05-17T11:18:17Z 2017 Artigo SILVA-SILVA, Jo?o Victor et al. Anti-promastigote activity of the amazon plants. Journal of Pharmacy and Pharmacology, v. 5, n. 9, p. 654-660, Sept. 2017. 2328-2150 http://patua.iec.gov.br//handle/iec/3692 10.17265/2328-2150/2017.09.007 eng Acesso Aberto application/pdf David Publishing
institution	Instituto Evandro Chagas (IEC)
collection	PATUA
language	eng
topic	Fitoterapia / m?todos Plantas Medicinais / qu?mica Extratos Vegetais / qu?mica Leishmania / efeitos dos f?rmacos Himatanthus articulatus Fasciculata parahancornia Montrichardia linifera Physalis angulata
spellingShingle	Fitoterapia / m?todos Plantas Medicinais / qu?mica Extratos Vegetais / qu?mica Leishmania / efeitos dos f?rmacos Himatanthus articulatus Fasciculata parahancornia Montrichardia linifera Physalis angulata Silva-Silva, Jo?o Victor Anti-promastigote activity of the amazon plants
topic_facet	Fitoterapia / m?todos Plantas Medicinais / qu?mica Extratos Vegetais / qu?mica Leishmania / efeitos dos f?rmacos Himatanthus articulatus Fasciculata parahancornia Montrichardia linifera Physalis angulata
description	This study evaluated in vitro activity of ethanol extract, fractions, and isolated substance from Amazon species against promastigotes of L. amazonensis. The ethanol extracts were concentrated and fractionation. The anti-promastigote activity was evaluated through the cell viability assessment method (MTT). The ethanol extract, fractions, and isolated substance from Himatanthus articulatus and Parahancornia fasciculata were inactive in promastigote of L. amazonensis, as the ethanol extract of Physalis angulata. The hexane fractions from different parts of Montrichardia linifera showed anti-promastigote activity probably due to the presence of steroids and terpenes. All species in studies were inactive, except of M. linifera. The few polar constituents can be responsible for the activity. Therefore, the isolation and purification of the active on L. amazonensis promastigotes are urgently required.
format	Artigo
author	Silva-Silva, Jo?o Victor
author2	Monteiro, R. C. S. Brigido, H. P. C. Vale, Valdicley Vieira Silvestre, J. V. Silva, N. C. S. Silveira, Fernando Tobias Marinho, A. M. R. Dolabela, Maria Fani
author2Str	Monteiro, R. C. S. Brigido, H. P. C. Vale, Valdicley Vieira Silvestre, J. V. Silva, N. C. S. Silveira, Fernando Tobias Marinho, A. M. R. Dolabela, Maria Fani
title	Anti-promastigote activity of the amazon plants
title_short	Anti-promastigote activity of the amazon plants
title_full	Anti-promastigote activity of the amazon plants
title_fullStr	Anti-promastigote activity of the amazon plants
title_full_unstemmed	Anti-promastigote activity of the amazon plants
title_sort	anti-promastigote activity of the amazon plants
publisher	David Publishing
publishDate	2019
url	http://patua.iec.gov.br//handle/iec/3692
_version_	1717584376208818176
score	11.755432

Anti-promastigote activity of the amazon plants

Registros relacionados