Low prevalence of HIV-1 integrase resistance among antiretroviral-naive patients newly diagnosed with HIV-1 from Bel?m, Par?, Amazon region of Brazil
We described the HIV-1 subtypes and the frequency of resistance mutations in HIV-1 integrase region among antiretroviral-naive patients with HIV/AIDS from Bel?m, Par?, Amazon region of Brazil. The partial integrase gene sequence of 59 antiretroviral-naive HIV-1 infected patients was amplified and se...
| Autor principal: | Torres, Maria K. S |
|---|---|
| Outros Autores: | Avelino, Maria E. S, Irias, Susan F, Barbosa, Mike S, Pereira, Danilo L. A, Lima, Ana B. F, Lemos, Poliana da Silva, Lima, Clayton Pereira Silva de, Oliveira, Renato R. M, Fr?nces, Regiane S. K, Vianez J?nior, Jo?o L?dio da Silva Gon?alves, Machado, Luiz Fernando Almeida |
| Grau: | Artigo |
| Idioma: | eng |
| Publicado em: |
Mary Ann Liebert
2020
|
| Assuntos: | |
| Acesso em linha: |
http://patua.iec.gov.br//handle/iec/4053 |
| id |
ir-iec-4053 |
|---|---|
| recordtype |
dspace |
| spelling |
ir-iec-40532020-02-21T12:44:52Z Low prevalence of HIV-1 integrase resistance among antiretroviral-naive patients newly diagnosed with HIV-1 from Bel?m, Par?, Amazon region of Brazil Torres, Maria K. S Avelino, Maria E. S Irias, Susan F Barbosa, Mike S Pereira, Danilo L. A Lima, Ana B. F Lemos, Poliana da Silva Lima, Clayton Pereira Silva de Oliveira, Renato R. M Fr?nces, Regiane S. K Vianez J?nior, Jo?o L?dio da Silva Gon?alves Machado, Luiz Fernando Almeida HIV-1 / patogenicidade Terapia Antirretroviral de Alta Atividade Infec??es por HIV S?ndrome de Imunodefici?ncia Adquirida Integrase de HIV Integrases We described the HIV-1 subtypes and the frequency of resistance mutations in HIV-1 integrase region among antiretroviral-naive patients with HIV/AIDS from Bel?m, Par?, Amazon region of Brazil. The partial integrase gene sequence of 59 antiretroviral-naive HIV-1 infected patients was amplified and sequenced. Genotypic analyses revealed the absence of major resistance-associated mutations to integrase but minor polymorphic mutations were present in 44.1% of patients and M50I polymorphism was the more prevalent. 2020-02-20T17:41:06Z 2020-02-20T17:41:06Z 2020 Artigo TORRES, Maria K. S. et al. Low prevalence of HIV-1 integrase resistance among antiretroviral-naive patients newly diagnosed with HIV-1 from Bel?m, Par?, Amazon region of Brazil. AIDS Research and Human Retroviruses, v. 36, n. 2, p. 97-98, Feb. 2020. 1931-8405 http://patua.iec.gov.br//handle/iec/4053 10.1089/AID.2019.019 eng Acesso Embargado application/pdf Mary Ann Liebert |
| institution |
Instituto Evandro Chagas (IEC) |
| collection |
PATUA |
| language |
eng |
| topic |
HIV-1 / patogenicidade Terapia Antirretroviral de Alta Atividade Infec??es por HIV S?ndrome de Imunodefici?ncia Adquirida Integrase de HIV Integrases |
| spellingShingle |
HIV-1 / patogenicidade Terapia Antirretroviral de Alta Atividade Infec??es por HIV S?ndrome de Imunodefici?ncia Adquirida Integrase de HIV Integrases Torres, Maria K. S Low prevalence of HIV-1 integrase resistance among antiretroviral-naive patients newly diagnosed with HIV-1 from Bel?m, Par?, Amazon region of Brazil |
| topic_facet |
HIV-1 / patogenicidade Terapia Antirretroviral de Alta Atividade Infec??es por HIV S?ndrome de Imunodefici?ncia Adquirida Integrase de HIV Integrases |
| description |
We described the HIV-1 subtypes and the frequency of resistance mutations in HIV-1 integrase region among antiretroviral-naive patients with HIV/AIDS from Bel?m, Par?, Amazon region of Brazil. The partial integrase gene sequence of 59 antiretroviral-naive HIV-1 infected patients was amplified and sequenced. Genotypic analyses revealed the absence of major resistance-associated mutations to integrase but minor polymorphic mutations were present in 44.1% of patients and M50I polymorphism was the more prevalent. |
| format |
Artigo |
| author |
Torres, Maria K. S |
| author2 |
Avelino, Maria E. S Irias, Susan F Barbosa, Mike S Pereira, Danilo L. A Lima, Ana B. F Lemos, Poliana da Silva Lima, Clayton Pereira Silva de Oliveira, Renato R. M Fr?nces, Regiane S. K Vianez J?nior, Jo?o L?dio da Silva Gon?alves Machado, Luiz Fernando Almeida |
| author2Str |
Avelino, Maria E. S Irias, Susan F Barbosa, Mike S Pereira, Danilo L. A Lima, Ana B. F Lemos, Poliana da Silva Lima, Clayton Pereira Silva de Oliveira, Renato R. M Fr?nces, Regiane S. K Vianez J?nior, Jo?o L?dio da Silva Gon?alves Machado, Luiz Fernando Almeida |
| title |
Low prevalence of HIV-1 integrase resistance among antiretroviral-naive patients newly diagnosed with HIV-1 from Bel?m, Par?, Amazon region of Brazil |
| title_short |
Low prevalence of HIV-1 integrase resistance among antiretroviral-naive patients newly diagnosed with HIV-1 from Bel?m, Par?, Amazon region of Brazil |
| title_full |
Low prevalence of HIV-1 integrase resistance among antiretroviral-naive patients newly diagnosed with HIV-1 from Bel?m, Par?, Amazon region of Brazil |
| title_fullStr |
Low prevalence of HIV-1 integrase resistance among antiretroviral-naive patients newly diagnosed with HIV-1 from Bel?m, Par?, Amazon region of Brazil |
| title_full_unstemmed |
Low prevalence of HIV-1 integrase resistance among antiretroviral-naive patients newly diagnosed with HIV-1 from Bel?m, Par?, Amazon region of Brazil |
| title_sort |
low prevalence of hiv-1 integrase resistance among antiretroviral-naive patients newly diagnosed with hiv-1 from bel?m, par?, amazon region of brazil |
| publisher |
Mary Ann Liebert |
| publishDate |
2020 |
| url |
http://patua.iec.gov.br//handle/iec/4053 |
| _version_ |
1717584403536805888 |
| score |
11.755432 |