Artigo

Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei

The antifungal and anti-germ tube formation activity of Rosmarinus officinalis Linn. essential oil was tested against four Candida strains (C. albicans, C. dubliniensis, C. parapsilosis and C. krusei). Inhibition halo sizes and minimal inhibitory concentrations (MIC) were obtained using radial diffu...

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Autor principal: Gauch, Lurdete Maria Rocha
Outros Autores: Pedrosa, Simone Soares, Esteves, Renata Antunes, Silveira-Gomes, Fabíola, Gurgel, Ely Simone Cajueiro, Arruda, Alberto Cardoso, Marques-da-Silva, Silvia Helena
Grau: Artigo
Idioma: eng
Publicado em: Museu Paraense Emilio Goeldi 2018
Assuntos:
Candida Species
Rosmarinus officinalis
Essential Oil.
CNPQ::CIENCIAS BIOLOGICAS::BOTANICA
Acesso em linha: http://repositorio.museu-goeldi.br/handle/mgoeldi/1335
id ir-mgoeldi-1335
recordtype dspace
spelling ir-mgoeldi-13352019-07-17T18:23:49Z Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei Atividade antifúngica de Rosmarinus officinalis Linn. óleo essencial contra Candida albicans, Candida dubliniensis, Candida parapsilosis e Candida krusei Gauch, Lurdete Maria Rocha Pedrosa, Simone Soares Esteves, Renata Antunes Silveira-Gomes, Fabíola Gurgel, Ely Simone Cajueiro Arruda, Alberto Cardoso Marques-da-Silva, Silvia Helena Candida Species Rosmarinus officinalis Essential Oil. CNPQ::CIENCIAS BIOLOGICAS::BOTANICA The antifungal and anti-germ tube formation activity of Rosmarinus officinalis Linn. essential oil was tested against four Candida strains (C. albicans, C. dubliniensis, C. parapsilosis and C. krusei). Inhibition halo sizes and minimal inhibitory concentrations (MIC) were obtained using radial diffusion and micro dilution tests, respectively. The minimal fungicidal concentration (MFC) was obtained from the MIC assay. Additionally, the effect of the essential oil on germ tube formation in C. albicans and C. dubliniensis was evaluated. The MIC50 ranged from 0.5% to 2%, while the MFC ranged from 1% to 2%. We observed total inhibition of germ tube formation in C. albicans and C. dubliniensis. The R. officinalis Linn. essential oil displayed powerful inhibitory and fungicidal activity against specific Candida strains. Atividade antifúngica e de formação de tubo anti-germinativo de Rosmarinus officinalis Linn. óleo essencial foi testado contra quatro cepas de Candida (C. albicans, C. dubliniensis, C. parapsilosis e C. krusei). Os tamanhos de halo de inibição e as concentrações inibitórias mínimas (CIM) foram obtidos usando testes de difusão radial e de micro-diluição, respectivamente. A concentração fungicida mínima (MFC) foi obtida a partir do ensaio MIC. Adicionalmente, o efeito do óleo essencial na formação do tubo germinativo em C. albicans e C. dubliniensis foi avaliado. O MIC50 variou de 0,5% a 2%, enquanto o MFC variou de 1% a 2%. Observamos inibição total da formação de tubo germinativo em C. albicans e C. dubliniensis. O R. officinalis Linn. óleo essencial apresentou poderosa atividade inibitória e fungicida contra cepas específicas de Candida. 2018-11-22T12:57:06Z 2018-10-30 2018-11-22T12:57:06Z 2014-03-20 Artigo de Periódico http://repositorio.museu-goeldi.br/handle/mgoeldi/1335 eng Revista Pan-Amazônica de Saúde Acesso Aberto application/pdf Museu Paraense Emilio Goeldi Brasil MPEG
institution Repositório Institucional - Museu Paraense Emílio Goeldi
collection RepositorioEmilioGoeldi
language eng
topic Candida Species
Rosmarinus officinalis
Essential Oil.
CNPQ::CIENCIAS BIOLOGICAS::BOTANICA
spellingShingle Candida Species
Rosmarinus officinalis
Essential Oil.
CNPQ::CIENCIAS BIOLOGICAS::BOTANICA
Gauch, Lurdete Maria Rocha
Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei
topic_facet Candida Species
Rosmarinus officinalis
Essential Oil.
CNPQ::CIENCIAS BIOLOGICAS::BOTANICA
description The antifungal and anti-germ tube formation activity of Rosmarinus officinalis Linn. essential oil was tested against four Candida strains (C. albicans, C. dubliniensis, C. parapsilosis and C. krusei). Inhibition halo sizes and minimal inhibitory concentrations (MIC) were obtained using radial diffusion and micro dilution tests, respectively. The minimal fungicidal concentration (MFC) was obtained from the MIC assay. Additionally, the effect of the essential oil on germ tube formation in C. albicans and C. dubliniensis was evaluated. The MIC50 ranged from 0.5% to 2%, while the MFC ranged from 1% to 2%. We observed total inhibition of germ tube formation in C. albicans and C. dubliniensis. The R. officinalis Linn. essential oil displayed powerful inhibitory and fungicidal activity against specific Candida strains.
format Artigo
author Gauch, Lurdete Maria Rocha
author2 Pedrosa, Simone Soares
Esteves, Renata Antunes
Silveira-Gomes, Fabíola
Gurgel, Ely Simone Cajueiro
Arruda, Alberto Cardoso
Marques-da-Silva, Silvia Helena
author2Str Pedrosa, Simone Soares
Esteves, Renata Antunes
Silveira-Gomes, Fabíola
Gurgel, Ely Simone Cajueiro
Arruda, Alberto Cardoso
Marques-da-Silva, Silvia Helena
title Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei
title_short Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei
title_full Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei
title_fullStr Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei
title_full_unstemmed Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei
title_sort antifungal activity of rosmarinus officinalis linn. essential oil against candida albicans, candida dubliniensis, candida parapsilosis and candida krusei
publisher Museu Paraense Emilio Goeldi
publishDate 2018
url http://repositorio.museu-goeldi.br/handle/mgoeldi/1335
_version_ 1787135668405665792
score 11.755432

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