Introduction: Lacaziose is a chronic disease, localized or disseminated, characterized by
lesions similar to a keloid, nodular or verrucous. It is a disease caused by infection Lacazia
loboi (L. loboi) that affects mainly rural workers who live in contact with vegetation and soil,
such as rubber tappers in the Amazon. Maybe that’s why it is more frequent in males. By
October 1995 there were 418 reported cases, with 255 of them in Brazil. General Objetive:
To describe the clinical, epidemiological and therapeutic in patients diagnosed with lacaziose
Department of Dermatology Federal University of Pará (SDUFPA). Specific Objectives: To
describe the sociodemographic profile of carriers of lacaziose; identify possible ways of
transmission of the disease; to observe the dermatological characteristics of the presented
cases; knowing the therapeutic response of patients; assess treatment compliance.
Methodology: This is a clinical, epidemiological, cross-sectional, retrospective, descriptive
and observational study using medical records of patients in lacaziose SDUFPA from January
1997 to july 2011. Results: We analyzed 16 patients in lacaziose SDUFPA. There was a
predominance of males (81.25%), age of more than 60 years (56.25%) and from the interior of
Pará (87.5%), the annual distribution of cases showed homogenous over the 14 years, most of
the visits occurred in 2008 (18.75%). The highest prevalence of cases was observed in rural
workers (62.5%), mostly married (56.25%). The lower limb injuries were most common
(47%), with predominance of localized lesions (61.9%), followed by disseminated (24%) and
more was found to keloid (61.1%). Pruritus was the most frequent symptom (62.5%) and
ulceration was the main complication (55.5%). The combination of medical and surgical
treatment predominated (43.7%). Clofazimine was the most used drug (31.2%) and the
procedure most widely adopted surgical excision (76.9%). Recurrence after surgical treatment
occurred in most patients (80%). Conclusion: Lacaziose is a little known disease in relation to
transmission, pathophysiology and treatment. It is necessary that more studies be conducted in
orde to discover the source of infection and interrupt the chain of transmission, and allow the
emergence of more effective therapeutic measures.
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