Introduction: DM1 (diabetes mellitus 1) is a chronic endocrine-metabolic disorder
resulting from the destruction of insulin-producing pancreatic beta cells. Loss of glycemic
homeostasis can lead to acute and chronic complications. DM1 and its complications are
factors that can significantly compromise quality of life (QoL), causing greater impact on
multiple dimensions of the patient's life and resulting in lower therapeutic adherence. In
view of this, the assessment of QoL in DM1 is shown to be a valuable tool in the
systematization of care for diabetic patients. Objectives: To evaluate the association
between complications and health-related quality of life (HRQoL) in patients with DM1.
Methods: This is an observational-descriptive, cross-sectional study, carried out after
approval by the Comitê de Ética em Pesquisa do Hospital Universitário João de Barros
Barreto (HUJBB). The study population consisted of 22 DM1 patients, followed up at the
Serviço do Ambulatório da Unidade de Endocrinologia do HUJBB and treated between
August 2021 and January 2022. The HRQoL assessment was performed using
questionnaires validated in the literature for this purpose, these being the Diabetes Quality
of Life Measure (DQOL) and EuroQol. Results: It was observed that 45.5% of the
participants had chronic complications related to DM1. The group with complications
had higher scores in the DQOL impact domain when compared to those without
complications (M1 51 and M2 37, respectively), in addition to lower scores in the EQ 5D-5L (M1 0.609 and M2 0.814) and EQ-VAS (M1 66 and M2 80). Conclusion: DM1
patients with complications and previous hospitalization were more likely to have low
HRQoL.
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