Trabalho de Conclusão de Curso - Graduação

Fenótipo metabólico de pacientes adultos atendidos no ambulatório de nutrição de um hospital escola

Metabolic syndrome is a designation that does not refer to a specific clinical condition, but to a set of cardiovascular risk factors, which tend to cluster in an individual. The present study aimed to identify the metabolic phenotype of adult patients treated at the nutrition clinic of a teachi...

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Autor principal: MUYANDA, Hanse Kasongo
Grau: Trabalho de Conclusão de Curso - Graduação
Publicado em: 2023
Assuntos:
Acesso em linha: https://bdm.ufpa.br:8443/jspui/handle/prefix/5915
Resumo:
Metabolic syndrome is a designation that does not refer to a specific clinical condition, but to a set of cardiovascular risk factors, which tend to cluster in an individual. The present study aimed to identify the metabolic phenotype of adult patients treated at the nutrition clinic of a teaching hospital in the city of Belém­Pará. This is a cross­sectional, quantitative and descriptive study, based on the collection of secondary data from electronic medical records. Data on sociodemographic (gender and age), clinical (clinical diagnosis), anthropometric (height, weight, BMI and WC), and metabolic variables (fasting glucose, triglycerides, total cholesterol, HDL­chol, LDL­chol, and not HDL­chol). The statistical treatment was performed using the open programming language Python, allowing to automate the analysis with lines of code in the integrated development environment Jupyter Notebook. Analytical statistics comprised a nonparametric (G test) or parametric (Chi­square) comparison test to establish a statistically significant difference between frequencies, and a nonparametric (Spearman) or parametric (Pearson) correlation test to analyze continuous quantitative variables. In all tests applied, a significance level < 0.05% was adopted. The medical records of 114 patients were analyzed, among which 78.9% were women. There was a higher prevalence of diabetes and hypertension, both with 42.1%. One hundred and one patients (88.6%) had a BMI greater than or equal to 25kg/m² (p<0.001), among which 60.4% were overweight (p<0.05) and 22.8% were obese (p <0.001), significantly compared to obesity II (6.9%) and III (9.9%). The frequency of glucose inadequacy was significantly higher among men (66.7%) than among women (38.9%). Considering the lipid profile, there was no significant difference between adequacy and inadequacy of triglycerides, in both sexes. However, there was a higher frequency of inadequacy of total cholesterol among women (52.2%), while men had a higher prevalence of adequacy (66.7%). There was significant prevalence (p<0.05) of low HDL­chol, high LDL chol and non­HDL­chol high in both sexes, being more prevalent among women. A strong and significant correlation was found between LDL­cho and total cholesterol (r=0.89, p˂0.05). It is concluded that the studied population presented high cardiovascular risk factors, and educational actions should be implemented to avoid the worsening of their clinical condition.