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Trabalho de Conclusão de Curso - Graduação
Fenótipo metabólico de pacientes adultos atendidos no ambulatório de nutrição de um hospital escola
Metabolic syndrome is a designation that does not refer to a specific clinical condition, but to a set of cardiovascular risk factors, which tend to cluster in an individual. The present study aimed to identify the metabolic phenotype of adult patients treated at the nutrition clinic of a teachi...
Autor principal: | MUYANDA, Hanse Kasongo |
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Grau: | Trabalho de Conclusão de Curso - Graduação |
Publicado em: |
2023
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Assuntos: | |
Acesso em linha: |
https://bdm.ufpa.br:8443/jspui/handle/prefix/5915 |
Resumo: |
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Metabolic syndrome is a designation that does not refer to a specific clinical condition, but to a
set of cardiovascular risk factors, which tend to cluster in an individual. The present study aimed
to identify the metabolic phenotype of adult patients treated at the nutrition clinic of a teaching
hospital in the city of BelémPará. This is a crosssectional, quantitative and descriptive study,
based on the collection of secondary data from electronic medical records. Data on
sociodemographic (gender and age), clinical (clinical diagnosis), anthropometric (height,
weight, BMI and WC), and metabolic variables (fasting glucose, triglycerides, total cholesterol,
HDLchol, LDLchol, and not HDLchol). The statistical treatment was performed using the
open programming language Python, allowing to automate the analysis with lines of code in
the integrated development environment Jupyter Notebook. Analytical statistics comprised a
nonparametric (G test) or parametric (Chisquare) comparison test to establish a statistically
significant difference between frequencies, and a nonparametric (Spearman) or parametric
(Pearson) correlation test to analyze continuous quantitative variables. In all tests applied, a
significance level < 0.05% was adopted. The medical records of 114 patients were analyzed,
among which 78.9% were women. There was a higher prevalence of diabetes and hypertension,
both with 42.1%. One hundred and one patients (88.6%) had a BMI greater than or equal to
25kg/m² (p<0.001), among which 60.4% were overweight (p<0.05) and 22.8% were obese (p
<0.001), significantly compared to obesity II (6.9%) and III (9.9%). The frequency of glucose
inadequacy was significantly higher among men (66.7%) than among women (38.9%).
Considering the lipid profile, there was no significant difference between adequacy and
inadequacy of triglycerides, in both sexes. However, there was a higher frequency of
inadequacy of total cholesterol among women (52.2%), while men had a higher prevalence of
adequacy (66.7%). There was significant prevalence (p<0.05) of low HDLchol, high LDL chol and nonHDLchol high in both sexes, being more prevalent among women. A strong and
significant correlation was found between LDLcho and total cholesterol (r=0.89, p˂0.05). It is
concluded that the studied population presented high cardiovascular risk factors, and
educational actions should be implemented to avoid the worsening of their clinical condition. |