Trabalho de Conclusão de Curso - Graduação

Análise dos aspectos epidemiológicos dos portadores de hepatites b e c no estado do Pará

INTRODUCTION: Viral hepatitis are often silent systemic infectious diseases, where signs and symptoms become evident only after the disease has caused severe liver disease. They are caused by different viruses that have tropismo by the liver, with diverse epidemiological, clinical and laborato...

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Autor principal: GONÇALVES, Felipe André Brito
Outros Autores: SILVA, Lucas Pereira da
Grau: Trabalho de Conclusão de Curso - Graduação
Publicado em: 2023
Assuntos:
Acesso em linha: https://bdm.ufpa.br:8443/jspui/handle/prefix/6063
Resumo:
INTRODUCTION: Viral hepatitis are often silent systemic infectious diseases, where signs and symptoms become evident only after the disease has caused severe liver disease. They are caused by different viruses that have tropismo by the liver, with diverse epidemiological, clinical and laboratory characteristics. According to the World Health Organization (2017), about 390 million people in the world live with chronic hepatitis B virus - HBV (240 million) or the hepatitis C virus - HCV (150 million). OBJECTIVES: The objective of the present study was to describe the epidemiological and laboratory profile of patients with hepatitis B and C virus. More specifically, the variables of the epidemiological profile (sex and age group) and laboratory variables (liver tests) hepatitis B and C virus carriers assisted by the Hepatitis Clinic of the Nucleus of Tropical Medicine (NMT) of the Federal University of Pará (UFPA). METHODOLOGY: This is an epidemiological, comparative, analytical cross sectional study based on the use of secondary data (medical records) from the NMT / UFPA Hepatitis Clinic. The collection includes the following variables: epidemiological (sex, age, age range and pattern of hepatic elastography); (AST / ALT, GGT, Alkaline Phosphatase, Total Bilirubins and Fractions, Total Cholesterol and Fractions, Triglycerides, and Blood Glucose), as well as hemoglobin, leukocytes, platelets, urea, creatinine, AST and ALT. RESULTS:Hepatitis C (67.11%) and Hepatitis B (32.89%). It can also be observed that the prevalence of the disease was more prevalent in males (63.16%) and in people aged between 50 and 60 Comparative analysis of the epidemiological and laboratory profile between the two groups of hepatitis C and Hepatitis B showed that there were no statistically significant differences between the two groups, regarding epidemiological variables (39.47%). (P <0.0001) and ALT (p = 0.003). It can be evidenced that in the group of individuals with Hepatitis C the transaminases were significantly higher and outside the values considered normal. CONCLUSION: Through the results of the present study, it can be observed that the most frequent cases of hepatitis in the sample were type C, being more frequent in men, at the age of 50 years. No difference in the epidemiological profile between the hepatitis B and C groups was found, only in AST and ALT values, significantly higher in patients with hepatitis C.