Artigo

Secondary metabolites from Rubiaceae species

This study describes some characteristics of the Rubiaceae family pertaining to the occurrence and distribution of secondary metabolites in the main genera of this family. It reports the review of phytochemical studies addressing all species of Rubiaceae, published between 1990 and 2014. Iridoids, a...

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Autor principal: Martins, Daiane
Outros Autores: Nunez, C. V.
Grau: Artigo
Idioma: English
Publicado em: Molecules 2020
Assuntos:
Acesso em linha: https://repositorio.inpa.gov.br/handle/1/15890
id oai:repositorio:1-15890
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spelling oai:repositorio:1-15890 Secondary metabolites from Rubiaceae species Martins, Daiane Nunez, C. V. Alkaloid Anthraquinone Derivative Iridoid Biosynthesis Chemistry Metabolism Rubiaceae Alkaloids Anthraquinones Iridoids Rubiaceae This study describes some characteristics of the Rubiaceae family pertaining to the occurrence and distribution of secondary metabolites in the main genera of this family. It reports the review of phytochemical studies addressing all species of Rubiaceae, published between 1990 and 2014. Iridoids, anthraquinones, triterpenes, indole alkaloids as well as other varying alkaloid subclasses, have shown to be the most common. These compounds have been mostly isolated from the genera Uncaria, Psychotria, Hedyotis, Ophiorrhiza and Morinda. The occurrence and distribution of iridoids, alkaloids and anthraquinones point out their chemotaxonomic correlation among tribes and subfamilies. From an evolutionary point of view, Rubioideae is the most ancient subfamily, followed by Ixoroideae and finally Cinchonoideae. The chemical biosynthetic pathway, which is not so specific in Rubioideae, can explain this and large amounts of both iridoids and indole alkaloids are produced. In Ixoroideae, the most active biosysthetic pathway is the one that produces iridoids; while in Cinchonoideae, it produces indole alkaloids together with other alkaloids. The chemical biosynthetic pathway now supports this botanical conclusion. © 2015 by the authors; licensee MDPI. 2020-05-19T21:03:16Z 2020-05-19T21:03:16Z 2015 Artigo https://repositorio.inpa.gov.br/handle/1/15890 10.3390/molecules200713422 en Volume 20, Número 7, Pags. 13422-13495 Attribution-NonCommercial-NoDerivs 3.0 Brazil http://creativecommons.org/licenses/by-nc-nd/3.0/br/ application/pdf Molecules
institution Instituto Nacional de Pesquisas da Amazônia - Repositório Institucional
collection INPA-RI
language English
topic Alkaloid
Anthraquinone Derivative
Iridoid
Biosynthesis
Chemistry
Metabolism
Rubiaceae
Alkaloids
Anthraquinones
Iridoids
Rubiaceae
spellingShingle Alkaloid
Anthraquinone Derivative
Iridoid
Biosynthesis
Chemistry
Metabolism
Rubiaceae
Alkaloids
Anthraquinones
Iridoids
Rubiaceae
Martins, Daiane
Secondary metabolites from Rubiaceae species
topic_facet Alkaloid
Anthraquinone Derivative
Iridoid
Biosynthesis
Chemistry
Metabolism
Rubiaceae
Alkaloids
Anthraquinones
Iridoids
Rubiaceae
description This study describes some characteristics of the Rubiaceae family pertaining to the occurrence and distribution of secondary metabolites in the main genera of this family. It reports the review of phytochemical studies addressing all species of Rubiaceae, published between 1990 and 2014. Iridoids, anthraquinones, triterpenes, indole alkaloids as well as other varying alkaloid subclasses, have shown to be the most common. These compounds have been mostly isolated from the genera Uncaria, Psychotria, Hedyotis, Ophiorrhiza and Morinda. The occurrence and distribution of iridoids, alkaloids and anthraquinones point out their chemotaxonomic correlation among tribes and subfamilies. From an evolutionary point of view, Rubioideae is the most ancient subfamily, followed by Ixoroideae and finally Cinchonoideae. The chemical biosynthetic pathway, which is not so specific in Rubioideae, can explain this and large amounts of both iridoids and indole alkaloids are produced. In Ixoroideae, the most active biosysthetic pathway is the one that produces iridoids; while in Cinchonoideae, it produces indole alkaloids together with other alkaloids. The chemical biosynthetic pathway now supports this botanical conclusion. © 2015 by the authors; licensee MDPI.
format Artigo
author Martins, Daiane
author2 Nunez, C. V.
author2Str Nunez, C. V.
title Secondary metabolites from Rubiaceae species
title_short Secondary metabolites from Rubiaceae species
title_full Secondary metabolites from Rubiaceae species
title_fullStr Secondary metabolites from Rubiaceae species
title_full_unstemmed Secondary metabolites from Rubiaceae species
title_sort secondary metabolites from rubiaceae species
publisher Molecules
publishDate 2020
url https://repositorio.inpa.gov.br/handle/1/15890
_version_ 1787143174841434112
score 11.755432