Artigo

The influence of a TNF gene polymorphism on the severity of rheumatoid arthritis in the Brazilian Amazon

Purpose: The aim of this study was to investigate the influence of the TNF -308 G/A polymorphism in the promoter region of the tumor necrosis factor- α gene on the susceptibility and severity of rheumatoid arthritis (RA) in individuals from the Brazilian Amazon. Methods: A total of 323 individuals-1...

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Autor principal: Boechat, Antonio Luiz
Outros Autores: Boechat, Narjara de Oliveira, Ogusku, Maurício Morishi, Alencar, Mariana Raposo, Abensur, Themis da Costa, Neto, José Cardoso, Amorim, Leilian de Souza, Oliveira, Lívia Moura de, Sadahiro, Aya, Santos, Maria Cristina dos
Grau: Artigo
Idioma: English
Publicado em: Cytokine 2020
Assuntos:
Disease Modifying Antirheumatic Drug
Dna
Rheumatoid Factor
Tumor Necrosis Factor-alpha
Tumor Necrosis Factor Alpha Inhibitor
Adult
Age
Aged
Brasil
Clinical Feature
Confidence Interval
Controlled Study
Das28
Disease Duration
Disease Severity
Dna Extraction
Female
Gene Frequency
Polymorphism, Genetic
Genetic Susceptibility
Genotype
Health Assessment Questionnaire
Human
Logistic Regression Analysis
Major Clinical Study
Male
Polymerase Chain Reaction
Priority Journal
Promoter Region
Polymorphism, Restriction Fragment Length
Arthritis, Rheumatoid
Risk Assessment
Tnf Gene
Adolescent
Adult
Aged
Alleles
Arthritis, Rheumatoid
Brasil
Case-control Studies
Demography
Female
Genetic Predisposition To Disease
Humans
Joints
Logistic Models
Male
Middle Aged
Models, Genetic
Polymorphism, Single Nucleotide
Reproducibility Of Results
Roc Curve
Tumor Necrosis Factor-alpha
Young Adult
Acesso em linha: https://repositorio.inpa.gov.br/handle/1/17912

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