Bioavailability of vitamin a from peach palm (Bactris gasipaes H.B.K. and from Mango (Mangifera indica L.) in rats
The objective of the present study was to evaluate the bioavailability of vitamin A from peach palm and mango fruit by determining vitamin A and carotene reserves in the liver and plasma of rats. The experimental design consisted of an initial 36-day depletion period during which 42 male Wistar pups...
| Autor principal: | Yuyama, Lucia Kiyoko Ozaki |
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| Outros Autores: | Fávaro, Rosa Maria Duarte, Yuyama, Kaoru, Vannucchi, Hélio |
| Grau: | Artigo |
| Idioma: | English |
| Publicado em: |
Nutrition Research
2020
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| Acesso em linha: |
https://repositorio.inpa.gov.br/handle/1/19543 |
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oai:repositorio:1-19543 |
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oai:repositorio:1-19543 Bioavailability of vitamin a from peach palm (Bactris gasipaes H.B.K. and from Mango (Mangifera indica L.) in rats Yuyama, Lucia Kiyoko Ozaki Fávaro, Rosa Maria Duarte Yuyama, Kaoru Vannucchi, Hélio Carotene Retinol Animals Experiment Bioavailability Blood Level Female Fruit Liver Nonhuman Oral Drug Administration Priority Journal Rat The objective of the present study was to evaluate the bioavailability of vitamin A from peach palm and mango fruit by determining vitamin A and carotene reserves in the liver and plasma of rats. The experimental design consisted of an initial 36-day depletion period during which 42 male Wistar pups were suckled by dams receiving a basic vitamin A-free ration; after weaning (21 days), 36 young rats were then fed the same ration for a period of 15 days, with free access to water. The remaining 6 rats were sacrificed on the 15 day of life for measurement of basal liver vitamin A and carotene content. This initial period was followed by a 30-day repletion period during which the rats were divided into 6 groups of 6 animals each and submitted to the following treatments: diets containing 0.0, 2.0, 4.0 and 8.0 IU retinyl palmitate/g ration, respectively (control groups), and diets containing 4.0 IU vitamin A from mango and 4.0 IU vitamin A from peach palm/g ration (test groups). Mean basal vitamin A levels were 0.17 μg/g in liver and 3.50 μg% in plasma. At the end of the experiment, mean vitamin A levels in liver were 53.45 μg/g (peach palm group), 5.76 μg/g (mango group), and 9.52 μg/g (4 IU group), and vitamin A levels in plasma were 28.33 μg%, 29.80 μg% and 32.36 μg% for the same groups, respectively. Polynomial regression analysis applied to the data for the control groups showed a quadratic equation (Y=1.3803+0.9282x-0.0924x2; r2=0.9742) indicating that 5.02 IU vitamin A was sufficient to provide maximum vitamin A concentration in plasma. When the control and test groups were compared for liver and plasma carotene concentrations, a significant difference between groups was detected only for liver carotene. The present results show that peach palm vitamin A is highly biavailable, with 171% efficiency, followed by mango (82% efficiency) when compared with the control groups. © 1991 Pergamon Press plc. 2020-06-15T22:09:45Z 2020-06-15T22:09:45Z 1991 Artigo https://repositorio.inpa.gov.br/handle/1/19543 10.1016/S0271-5317(05)80694-3 en Volume 11, Número 10, Pags. 1167-1175 Restrito Nutrition Research |
| institution |
Instituto Nacional de Pesquisas da Amazônia - Repositório Institucional |
| collection |
INPA-RI |
| language |
English |
| topic |
Carotene Retinol Animals Experiment Bioavailability Blood Level Female Fruit Liver Nonhuman Oral Drug Administration Priority Journal Rat |
| spellingShingle |
Carotene Retinol Animals Experiment Bioavailability Blood Level Female Fruit Liver Nonhuman Oral Drug Administration Priority Journal Rat Yuyama, Lucia Kiyoko Ozaki Bioavailability of vitamin a from peach palm (Bactris gasipaes H.B.K. and from Mango (Mangifera indica L.) in rats |
| topic_facet |
Carotene Retinol Animals Experiment Bioavailability Blood Level Female Fruit Liver Nonhuman Oral Drug Administration Priority Journal Rat |
| description |
The objective of the present study was to evaluate the bioavailability of vitamin A from peach palm and mango fruit by determining vitamin A and carotene reserves in the liver and plasma of rats. The experimental design consisted of an initial 36-day depletion period during which 42 male Wistar pups were suckled by dams receiving a basic vitamin A-free ration; after weaning (21 days), 36 young rats were then fed the same ration for a period of 15 days, with free access to water. The remaining 6 rats were sacrificed on the 15 day of life for measurement of basal liver vitamin A and carotene content. This initial period was followed by a 30-day repletion period during which the rats were divided into 6 groups of 6 animals each and submitted to the following treatments: diets containing 0.0, 2.0, 4.0 and 8.0 IU retinyl palmitate/g ration, respectively (control groups), and diets containing 4.0 IU vitamin A from mango and 4.0 IU vitamin A from peach palm/g ration (test groups). Mean basal vitamin A levels were 0.17 μg/g in liver and 3.50 μg% in plasma. At the end of the experiment, mean vitamin A levels in liver were 53.45 μg/g (peach palm group), 5.76 μg/g (mango group), and 9.52 μg/g (4 IU group), and vitamin A levels in plasma were 28.33 μg%, 29.80 μg% and 32.36 μg% for the same groups, respectively. Polynomial regression analysis applied to the data for the control groups showed a quadratic equation (Y=1.3803+0.9282x-0.0924x2; r2=0.9742) indicating that 5.02 IU vitamin A was sufficient to provide maximum vitamin A concentration in plasma. When the control and test groups were compared for liver and plasma carotene concentrations, a significant difference between groups was detected only for liver carotene. The present results show that peach palm vitamin A is highly biavailable, with 171% efficiency, followed by mango (82% efficiency) when compared with the control groups. © 1991 Pergamon Press plc. |
| format |
Artigo |
| author |
Yuyama, Lucia Kiyoko Ozaki |
| author2 |
Fávaro, Rosa Maria Duarte Yuyama, Kaoru Vannucchi, Hélio |
| author2Str |
Fávaro, Rosa Maria Duarte Yuyama, Kaoru Vannucchi, Hélio |
| title |
Bioavailability of vitamin a from peach palm (Bactris gasipaes H.B.K. and from Mango (Mangifera indica L.) in rats |
| title_short |
Bioavailability of vitamin a from peach palm (Bactris gasipaes H.B.K. and from Mango (Mangifera indica L.) in rats |
| title_full |
Bioavailability of vitamin a from peach palm (Bactris gasipaes H.B.K. and from Mango (Mangifera indica L.) in rats |
| title_fullStr |
Bioavailability of vitamin a from peach palm (Bactris gasipaes H.B.K. and from Mango (Mangifera indica L.) in rats |
| title_full_unstemmed |
Bioavailability of vitamin a from peach palm (Bactris gasipaes H.B.K. and from Mango (Mangifera indica L.) in rats |
| title_sort |
bioavailability of vitamin a from peach palm (bactris gasipaes h.b.k. and from mango (mangifera indica l.) in rats |
| publisher |
Nutrition Research |
| publishDate |
2020 |
| url |
https://repositorio.inpa.gov.br/handle/1/19543 |
| _version_ |
1787145289816080384 |
| score |
11.653393 |