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Tese
Síntese e Caracterização de Membrana de Quitosana com Extrato de Banana Verde e Andiroba para Cicatrização de Lesões Epiteliais
Biomaterials must enable the surrounging healthy cells to grow and replace the matrix that constitutes the material. The application of other bioactives is being widely studied, as well as the incorporation of phytosan into chemical removal films in wound healing by different techniques. This stu...
Autor principal: | FERREIRA, Elisângela da Silva |
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Grau: | Tese |
Idioma: | por |
Publicado em: |
Universidade Federal do Pará
2022
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Assuntos: | |
Acesso em linha: |
http://repositorio.ufpa.br:8080/jspui/handle/2011/14076 |
Resumo: |
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Biomaterials must enable the surrounging healthy cells to grow and replace the matrix that
constitutes the material. The application of other bioactives is being widely studied, as well as
the incorporation of phytosan into chemical removal films in wound healing by different
techniques. This study aimed to synthesize and characterize chitosan membranes, green
banana peel extract and andiroba oil for application in epithelial devices. Membranes were
made in different compositions and characterization tests were carried out on the synthesizer.
Andiroba oil was added in pure form or oil-in-water (O/W) emulsion in the chitosan solution.
Higher in chitosan membranes with emulsion O/W, being 978.79 % e 423.64 %, in Nano M6
and Nano M11, respectively, after 24 hours of life in water. The highest percentage of
moisture was in M7 (24.9 ± 3.8 %) and the lowest in Nano M7 (13.46 ± 0.8 %). All samples
are hydrophilic, with lower values with banana peel extracts from the first decoction, M1
(24.0° ± 1.9°) and Nano M6 (23.7° ± 4.3°). Diffractograms are mostly amorphous material,
for the most part. Thermal analysis has greater stability of chitosan membranes synthesized
with banana peel extract and addition of andiroba oil. Spectroscopy showed characteristic
peaks and bands of sample components and interaction between these components, as well as
suggestion or encapsulation of the oil. The material first presented characteristics of
absorption of liquids and synthesized, in particular the membranes of banana extraction of the
day of decoction interaction and with addition of O/W emulsions, with greater possibility of
duration of its healing of composting epithelial deficiencies. |