Introduction: Health services, especially hospital institutions, are complex systems that involve several
risks, which can be exemplified by drug therapy. Investigation and knowledge of the factors that
determine the occurrence of medication errors allow for actions that strengthen safety in the medication
chain and the patient. Objective: Implement actions to improve safety, prescription, administration and
quality use of medicines in a hospital in Belém, Pará, Amazon. Method: The study took place in a
philanthropic hospital, located in the city of Belém, Pará. A quantitative study was carried out in the
action-research modality, data collection took place from December to January 2022, a semi-structured
form was applied to assess patient safety in dispensing, preparation and administration. Results and
discussion: 43 collaborators participated in this study, the analysis of the responses to the workers'
behavior allowed us to identify that the professionals reported unsatisfactory performance of 4 actions
(event notification; multidose recording; recording of temperature and medication by verbal order). From
the weaknesses found, strategies were presented to minimize these occurrences, they are: elaboration of
the safety protocol, use and administration of medications, standard operating procedure for high-alert
medication and protocol for the use of multi-dose medications. Conclusion: It was identified that despite
the knowledge of the risks and the need to guarantee patient safety through protocols for health services,
it was noticed the need to implement basic and fundamental actions through institutional standards and
routines, in accordance with with the local reality. Actions, when systematized, become possible
applications in the safety of medication use and contribute to reducing potential risks and promoting
safety and quality in the health work process.
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