Hypertension is a chronic disease that often accompanies diabetes mellitus and the
relationship between the two is complex. Like diabetes, it is an important cardiovascular risk
factor and microvascular complications, such as nephropathy and retinopathy, and has higher
health costs than diabetes itself. The treatment of hypertension in diabetes has been widely
debated and there is still a need to reach a consensus on treatment goals and strategies. The
objective of the present study was to develop a clinical protocol on the diagnosis and
treatment of hypertension in diabetes mellitus whose main foundation was its applicability in
the Brazilian public health system, focusing on medical adherence to recommendations, the
impact of applying the evidence in primary and secondary care, and the evolution of health
quality in these scenarios. To this end, an integrative literature review was carried out,
selecting health articles based on the quality of evidence located in the PUBMED database
and published in the last 20 years (2004-2024). Five researchers were responsible for
selecting those with the best quality of evidence. National and international guidelines and
works published by the UFPA diabetes clinical research group were also used. In the end, 106
articles were selected as theoretical references for preparing the protocol. The results were
synthesized in the form of a clinical protocol containing concise texts and teaching resources
(27 tables, 3 flowcharts and 1 figure) that will guarantee safety in clinical decision-making in
primary and secondary health care settings, configuring a practical guide on the topic in
question.
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