High prevalence of sexual Chlamydia trachomatis infection in young women from Maraj? Island, in the Brazilian Amazon
BACKGROUND: Chlamydia trachomatis is the most prevalent bacterial sexually transmitted infection (STI) in the world. Approximately 80% of infected women are asymptomatic, although this infection can lead to serious complications in the female reproductive tract. Few data on Chlamydia infection are a...
| Autor principal: | Santos, Leonardo Miranda dos |
|---|---|
| Outros Autores: | Vieira, Maria Renata Mendon?a dos Santos, Oliveira, J?ssica Fernanda Galdino, Trindade, Josinaide Quaresma, Brasiliense, Danielle Murici, Ferrari, Stephen Francis, Tsutsumi, Mihoko Yamamoto, Fuzii, Hellen Thais, Sousa J?nior, Edivaldo Costa, Ishikawa, Edna Aoba Yassui, Ishak, Ricardo, Sousa, Ma?sa Silva de |
| Grau: | Artigo |
| Idioma: | eng |
| Publicado em: |
Public Library of Science
2018
|
| Assuntos: | |
| Acesso em linha: |
http://patua.iec.gov.br//handle/iec/3544 |
| id |
ir-iec-3544 |
|---|---|
| recordtype |
dspace |
| spelling |
ir-iec-35442018-12-21T17:07:23Z High prevalence of sexual Chlamydia trachomatis infection in young women from Maraj? Island, in the Brazilian Amazon Santos, Leonardo Miranda dos Vieira, Maria Renata Mendon?a dos Santos Oliveira, J?ssica Fernanda Galdino Trindade, Josinaide Quaresma Brasiliense, Danielle Murici Ferrari, Stephen Francis Tsutsumi, Mihoko Yamamoto Fuzii, Hellen Thais Sousa J?nior, Edivaldo Costa Ishikawa, Edna Aoba Yassui Ishak, Ricardo Sousa, Ma?sa Silva de Chlamydia trachomatis / patogenicidade Infec??es por Chlamydia Infec??es por Chlamydia / virologia Comportamento Sexual Doen?as Bacterianas Sexualmente Transmiss?veis Assist?ncia ? Sa?de Arquip?lago do Maraj? (PA) BACKGROUND: Chlamydia trachomatis is the most prevalent bacterial sexually transmitted infection (STI) in the world. Approximately 80% of infected women are asymptomatic, although this infection can lead to serious complications in the female reproductive tract. Few data on Chlamydia infection are available in rural Amazonian communities. OBJECTIVES: To evaluate the prevalence of sexual C. trachomatis infection in women from Maraj? Archipelago communities in the Amazon region of Brazil and to identify associated factors and genotypes. METHODS: We utilized amplification of the ompA gene by nested PCR. Positive samples were genotyped by sequencing. Study participants completed a questionnaire on social, epidemiological, and reproductive health variables. A Poisson regression was used to evaluate the degree of association of these variables with the infection. RESULTS: The sexual infection by C. trachomatis was observed in 4% (16/393) of the subjects, and was more often found in women aged ?25 (14.3%; 95% CI = 2.83-35.47; p <0.001), and in women with a household income of less than one Brazilian monthly minimum wage (5.2%; 95% CI = 1.33-11.37; p = 0.014). The ompA gene was sequenced in 13 samples, revealing F genotypes (38.4%, n = 5), D (23%, n = 3), E (15.3%, n = 2), Ia (7.6%, N = 1), J (7.6%, n = 1) and B (7.6%, n = 1). CONCLUSIONS: We recorded a high prevalence of sexual infection by C. trachomatis in young and poor women from the interior of the Brazilian Amazon. This high prevalence and the frequencies of the main genotypes were similar to those found in major Brazilian urban centers. Our results reinforce the importance of the screening of this neglected infection, and the prevention of later sequelae in young women from rural and urban areas of Brazil. The present study was fully supported by grants from the Fundac??o Amazo?nia Paraense de Amparo a Pesquisa (FAPESPA ? ICAAF 014/2012) and Ministe?rio da Sau?de do Brasil (MS). 2018-12-21T16:41:59Z 2018-12-21T16:41:59Z 2018 Artigo SANTOS, Leonardo Miranda dos et al. High prevalence of sexual Chlamydia trachomatis infection in young women from Maraj? Island, in the Brazilian Amazon. PLoS One, v. 13, n. 11, e0207853, Nov. 2018. 1932-6203 http://patua.iec.gov.br//handle/iec/3544 10.1371/journal.pone.0207853 eng Acesso Aberto application/pdf Public Library of Science |
| institution |
Instituto Evandro Chagas (IEC) |
| collection |
PATUA |
| language |
eng |
| topic |
Chlamydia trachomatis / patogenicidade Infec??es por Chlamydia Infec??es por Chlamydia / virologia Comportamento Sexual Doen?as Bacterianas Sexualmente Transmiss?veis Assist?ncia ? Sa?de Arquip?lago do Maraj? (PA) |
| spellingShingle |
Chlamydia trachomatis / patogenicidade Infec??es por Chlamydia Infec??es por Chlamydia / virologia Comportamento Sexual Doen?as Bacterianas Sexualmente Transmiss?veis Assist?ncia ? Sa?de Arquip?lago do Maraj? (PA) Santos, Leonardo Miranda dos High prevalence of sexual Chlamydia trachomatis infection in young women from Maraj? Island, in the Brazilian Amazon |
| topic_facet |
Chlamydia trachomatis / patogenicidade Infec??es por Chlamydia Infec??es por Chlamydia / virologia Comportamento Sexual Doen?as Bacterianas Sexualmente Transmiss?veis Assist?ncia ? Sa?de Arquip?lago do Maraj? (PA) |
| description |
BACKGROUND: Chlamydia trachomatis is the most prevalent bacterial sexually transmitted infection (STI) in the world. Approximately 80% of infected women are asymptomatic, although this infection can lead to serious complications in the female reproductive tract. Few data on Chlamydia infection are available in rural Amazonian communities.
OBJECTIVES: To evaluate the prevalence of sexual C. trachomatis infection in women from Maraj? Archipelago communities in the Amazon region of Brazil and to identify associated factors and genotypes.
METHODS: We utilized amplification of the ompA gene by nested PCR. Positive samples were genotyped by sequencing. Study participants completed a questionnaire on social, epidemiological, and reproductive health variables. A Poisson regression was used to evaluate the degree of association of these variables with the infection.
RESULTS: The sexual infection by C. trachomatis was observed in 4% (16/393) of the subjects, and was more often found in women aged ?25 (14.3%; 95% CI = 2.83-35.47; p <0.001), and in women with a household income of less than one Brazilian monthly minimum wage (5.2%; 95% CI = 1.33-11.37; p = 0.014). The ompA gene was sequenced in 13 samples, revealing F genotypes (38.4%, n = 5), D (23%, n = 3), E (15.3%, n = 2), Ia (7.6%, N = 1), J (7.6%, n = 1) and B (7.6%, n = 1).
CONCLUSIONS: We recorded a high prevalence of sexual infection by C. trachomatis in young and poor women from the interior of the Brazilian Amazon. This high prevalence and the frequencies of the main genotypes were similar to those found in major Brazilian urban centers. Our results reinforce the importance of the screening of this neglected infection, and the prevention of later sequelae in young women from rural and urban areas of Brazil. |
| format |
Artigo |
| author |
Santos, Leonardo Miranda dos |
| author2 |
Vieira, Maria Renata Mendon?a dos Santos Oliveira, J?ssica Fernanda Galdino Trindade, Josinaide Quaresma Brasiliense, Danielle Murici Ferrari, Stephen Francis Tsutsumi, Mihoko Yamamoto Fuzii, Hellen Thais Sousa J?nior, Edivaldo Costa Ishikawa, Edna Aoba Yassui Ishak, Ricardo Sousa, Ma?sa Silva de |
| author2Str |
Vieira, Maria Renata Mendon?a dos Santos Oliveira, J?ssica Fernanda Galdino Trindade, Josinaide Quaresma Brasiliense, Danielle Murici Ferrari, Stephen Francis Tsutsumi, Mihoko Yamamoto Fuzii, Hellen Thais Sousa J?nior, Edivaldo Costa Ishikawa, Edna Aoba Yassui Ishak, Ricardo Sousa, Ma?sa Silva de |
| title |
High prevalence of sexual Chlamydia trachomatis infection in young women from Maraj? Island, in the Brazilian Amazon |
| title_short |
High prevalence of sexual Chlamydia trachomatis infection in young women from Maraj? Island, in the Brazilian Amazon |
| title_full |
High prevalence of sexual Chlamydia trachomatis infection in young women from Maraj? Island, in the Brazilian Amazon |
| title_fullStr |
High prevalence of sexual Chlamydia trachomatis infection in young women from Maraj? Island, in the Brazilian Amazon |
| title_full_unstemmed |
High prevalence of sexual Chlamydia trachomatis infection in young women from Maraj? Island, in the Brazilian Amazon |
| title_sort |
high prevalence of sexual chlamydia trachomatis infection in young women from maraj? island, in the brazilian amazon |
| publisher |
Public Library of Science |
| publishDate |
2018 |
| url |
http://patua.iec.gov.br//handle/iec/3544 |
| _version_ |
1717584348702572544 |
| score |
11.755432 |