Introduction: Nicotine is a psychostimulant present in tobacco. After being inhaled, a
substance attains knowledge in a few seconds. Previous studies that can be used to describe the
effects of the screen (delta, tenicotine, alpha, describe and gamma) However, there are drugs to
the drug profile during periods of withdrawal. Objectives: Characterize as electrophysiological
does not show changes in animals in nicotine withdrawal. Methodology: Thirty-six adult
Wistar rats were used, divided into the following groups: a) Control group (n=9); b) Nicotine
group (group treated with 1mg/kg nicotine via i.p.) (n=9); c) Group treated with nicotine (1
mg/ml) at a dose of 1 mg/kg i.p. for 14 days, with abstinence for 24 hours (n=9); d) Group
treated with nicotine (1 mg/ml) at a dose of 1 mg/kg i.p. for 14 days with abstinence of 48 hours
(n=9). Electroencephalic studies were performed to assess the graphic wave profile in each
group. Results: The group of previously sensitized rats that received nicotine in a definite way
and a greater increase in the amplitude of all waves found in studies were never increased,
differing from the results found in studies in studies. In the abstinent groups, there was an
increase in the power of delta waves, and a reduction in theta, alpha, beta and gamma waves.
Conclusion: As electrocorticographic changes corroborate the theory that the acute effects of
withdrawal may be related to electromagnetic waves. The profile described of the associates
during 24 and 48 hours of abstinence is in fact the series of the cognitive, mental, physical and
social performance. The description of changes implemented in this electrophysiological
spectrum is of interest for treatment studies for new treatment approaches for cigarette
addictions.
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